Students were taught the medicinal chemistry, pharmacology, and therapeutics of antiarrhythmic agents in the cardiology module presented in quarter 7 of the pharmd curriculum. A reversible lupus erythematouslike syndrome is most likely associated with this antiarrhythmic drug. Searches can be conducted on individual words or phrases, or by clicking on the links that organize the content by clinical. It is also good to remember the normal flow of electricity in the heart. Amiodarone has a broad spectrum of action on the heart. Both of these drugs cause sideeffects including dry mouth and sedation.
I also recommend kiss pharm to hammer the important facts once you understand the information. Answers are entered by clicking the button corresponding to your selection. Antiarrhythmic drugs do not improve the survival of patients with nonlifethreatening arrhythmias and may increase mortality, particularly in patients with structural heart disease. A short quiz based on the information in the antarrhythmic section. Antiarrhythmics are drugs that are used to treat abnormal heart rhythms resulting from irregular electrical activity of the heart. According to the vaughanwilliams classification of antiarrhythmic drugs it is a class iii drug, since it prolongs the repolarisation phase 3 of the action potential by blocking the potassium channels, thus increasing the effective refractory period. Antiarrhythmic drugs are used to prevent recurrent arrhythmias and restore. Coingestion of other drugs, including other antiarrhythmic drugs, may also affect the metabolism of a specific compound. The davis basic science cardiovascular laboratory focuses on various aspects of cardiac regeneration and preservation using molecularbased and biomaterialsbased. Antiarrhythmic drugs cheat sheet june 11, 2018 june 11, 2018 staff 0 comments antiarrhythmics are the drugs that affect the action potential of cardiac cells and are used to treat arrhythmias and restore normal rate and rhythm. Topic wise pharmacology questions and answers pdf 2020. Pdf on feb 9, 2018, gheorgheandrei dan and others published antiarrhythmic drugs clinical use and clinical decision making. Learn pharm quiz 2 pharmacology cardiovascular drugs with free interactive flashcards.
Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. To understand the action and classification of the antiarrhythmic drugs, it is first necessary to understand the ionic movements that underlie the cardiac action potential figure 1. Work to lower bp initially by decreasing peripheral vascular resistance b. Antihypertensives, vasodilators, angina drugs, cardiac glycosides. Induvidual properties of the antiarrhythmic drugs used in the therapy 7. Pdf to provide doctor of pharmacy pharmd students with highly integrated. Class ic drugs markedly depress phase 0 and extremely slows conduction but has little effect on the duration of action potential. Choose from 500 different sets of pharmacology antiarrhythmic drugs flashcards on quizlet. Antiarrhythmic drugs do not improve the survival of patients with nonlifethreatening arrhythmias and may increase mortality.
Class ib drugs somewhat depress phase 0 and shorten duration of action potential. Antiarrhythmic drugs are used to prevent recurrent arrhythmias and restore sinus rhythm in patients with cardiac arrhythmias. A consensus document from the european heart rhythm association ehra. This is the reason some sources may classify some antiarrhythmic agents differently to other sources.
Antiarrhythmic drugs basic concepts in pharmacology. Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of pharmaceuticals that are used to suppress abnormal rhythms of the heart cardiac arrhythmias, such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation. They also do a really great job on the antiarrhythmics and neuro drugs. This blog 50 cardiology pimp questions offers cardiology students an inside look at the top questions randomly asked during rounds, categorized by general, physical exam and ecg. When it is not possible to revert to normal sinus rhythm, drugs may be used to prevent more serious and possibly lethal arrhythmias from occurring. A contemporary view is that all drugs exert their desirable and undesirable effects by interacting with specific molecular targets. Ppt antiarrhythmic drugs powerpoint presentation free to. Many attempts have been made to classify antiarrhythmic agents.
Antiarrhythmic drugs free download as powerpoint presentation. The pervasiveness of polypharmacy makes the elderly vulnerable to adverse drugdrug interactions, including those involving antiarrhythmic drugs. Jan 07, 2020 brs pharmacology pdf 7th edition is designed for medical college students, dental college students, and different college students getting ready to enter the well being care professions. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Pdf teaching the pharmacology of antiarrhythmic drugs. However, there are several limitations with this system and some newer antiarrhythmics can be classified into more than one class. Using a television quiz show and classic board game format, students and the.
Pharmacology 501801 practice final exam february 22, 2005. Therapeutic window is the dosages of a medication therapeutic serum concentrations between. Learn more about shibboleth at brown brown university. Haloperidol has a higher systemic availability than thioridazine or chlorpromazine c. Brief summary of the therapeutic application of the antiarrhythmic drugs antiarrhythmic drugs. The contents of this site can be entered by several different routes using the navigation bar on the left. In this video we are providing 15 mcqs related to diuretics pharmacology, which is very important for the gpat, niper, esic pharmacist examination. May 06, 2019 in todays medical quiz, well be looking at antiarrhythmics, which are pharmaceuticals that help to ease abnormal rhythms of the heart, which can come about as a result of a number of different heart conditions. Multiple choice questions focused on the pharmacology classification and clinical activity of antiarrhythmic drugs. Antiarrhythmic drugs knowledge for medical students and. The ultimate goal of antiarrhythmic drug therapy is to restore normal rhythm and conduction. Pharmacology 501801 practice final exam february 22, 2005 for each of the following multiple choice questions, choose the most appropriate answer. Metabolites are important to the action of these drugs b.
Sep 25, 20 propranolol, acebutololesmolol have been aprroved for antiarrhythmic use. Learn pharmacology antiarrhythmic drugs with free interactive flashcards. Antiarrhythmic drugs practice questions this is a selfgrading exam. Lignociane is the drug of choice for the termination of vt and prevention of vf after cardioversion in the ischaemic setting.
Distribution of drugs to specific tissues a is independent of blood flow to the organ b is independent of the solubility of the drug in that tissue c depends on the unbound drug concentration gradient between blood and tissue d is increased for drugs that are strongly bound to plasma proteins e has no effect on the halflife of the. The long and growing list of non antiarrhythmic drugs associated with prolongation of the qt interval of the electrocardiogram has generated concern not only for regulatory interventions leading. Bp response to thiazides continues to increase at doses. The vaughanwilliams classification is a historic classification that groups antiarrhythmics into five main classes. Frequency dependent effect of antiarrhythmic drugs 5. Brown university authentication for webbased services. Sep 10, 2011 to provide doctor of pharmacy pharmd students with highly integrated, comprehensive and uptodate instruction related to the pharmacology of antiarrhythmic drugs. Antihypertensive drugs bja education oxford academic. The evidence base for the use of centrally acting drugs in hypertension is limited and adverse effects are common. Brs pharmacology pdf 7th edition download free medical. This describes the various antiarrythmic medications in terms of their mechanism of action with regard to the cardiac action. Professor of pharmacology, oman medical college, oman.
Which antiarrhythmic is not class ic agent a propafenone b tocainide c flecainide d encainide correct answer. Choose from 500 different sets of pharm quiz 2 pharmacology cardiovascular drugs flashcards on quizlet. Cv pharmacology welcome to cardiovascular pharmacology concepts. Class i antiarrhythmic drugs are all sodium channel blockers, but many of them, especially the class ia drugs, also have potassium channel blocker effects, including blockade of i to, i kr, and i ks. Table 6 lists some common antiarrhythmic drugs and suggests dosing modifications for the treatment of patients with coexisting diseases or patients receiving digoxin or other commonly used drugs. Antiarrhythmic drugs nursing pharmacology study guide. These drugs are classified based on their electrophysiological effect on the myocardium. Class ia drugs prolong ap class ib antiarrhytmic drugs shorten ap.
Jun 08, 2019 class ia drugs depress phase 0 and prolong duration of action potential. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Antiarrhythmic drug, administered iv, typically used to suppress ventricular arrhythmias associated with acute myocardial infarction. Contents preface, v aknowledgments, viii part 1 basic principles chapter 1 mechanisms of cardiac tachyarrhythmias, 3 chapter 2 introduction to antiarrhythmic drugs, 36 part 2 clinical features of antiarrhythmic drugs chapter 3 class i antiarrhythmic drugs, 55 chapter 4 class ii antiarrhythmic drugs. Its meant primarily to assist college students put together for licensing examinations, such because the usmle, however can be utilized for course assessment or as a supplementary textual. The kaplan videos are the gold standard for pharmacology. Cardiovascular pharmacology concepts is written primarily for students, teachers, and health professionals. Clonidine is an analgesic and sedative drug which reduces the minimum alveolar concentration of inhalation anaesthetic agents. Pharmacology questions and answers pdf free download for medical mbbs students objective mcqs interview lab viva multiple choice questions pharmacology faqs. Elimination half lives of these drugs range between 3 6 hours d. During intravenous therapy with ntg, if blood pressure bp drops and ischemia is not relieved, the addition of phenylephrine will allow coronary perfusion pressure cpp to be maintained while allowing higher doses of ntg to be used for ischemia relief. Pdf antiarrhythmic drugsclinical use and clinical decision.